Abstract

637 mice of the inbred C3H/St and C3HB/St strains bearing spontaneous adenocarcinomata have been used to study the influence on tumor growth rates and percentage of regressions of such tumors by tissue extracts derived from mice, mastomi, beef, bull and steer. The tumors can be divided into two classes depending upon whether they arose in the offspring of the non-treated series or in the offspring of mothers under treatment with liver extracts. The conclusions arrived at by this method are that the injection of a nursing mother with a specially prepared liver extract will affect: 1. the inhibition of growth rate of tumors and 2. the percentage of complete regressions of spontaneous tumors of mammary gland origin in mice.

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