Abstract
The possibility of complex formation between chloroquine and hyaluronate-protein has been investigated by a spectrophotomefric method. Interaction was observed between chloroquine and a hyaluronate-protein containing 3.4% protein, but no interaction occurred between chloroquine and hyaluronate-protein preparations containing 2.36 and 2.30% protein, respectively. The protein in two preparations appears to be tightly bound to the hyaluronate. The larger amount of protein in one of the preparations appears to be responsible for the binding process.
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