Abstract
The research to be described in this chapter has followed a distinctively different historical path than most neurotoxic research, and this is because of the underlying goals that have guided it. A fundamental question is why one would study the neurotoxic effects of drugs of abuse. One obvious answer is because this is an issue of great relevance to society. Another is because most of the closest models of mental disorders such as schizophrenia, or compulsive disorders, or depression, are based on drug models from addicts. This leads to the hope that understanding the effects of addiction will shed light on many other psychopathologies as well.
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