Abstract
From the foregoing data, the following general principles regarding the cranio-vertebral dynamics may be drawn: (1) The cerebrospinal fluid pressure directly follows either a change in venous pressure or a change in caliber of the cerebral vessels. It is only indirectly related to changes in arterial pressure. Thus, a rise in arterial pressure does not affect the cerebrospinal fluid pressure unless the venous pressure, as a result, becomes increased. The studies on postural alterations particularly stress the direct relationship between the cerebrospinal fluid and venous pressures. It may be stated that under ordinary physiological conditions, the venous pressure may be considered the chief factor in affecting the cerebrospinal fluid pressure. It is only under unusual conditions, such as severe metabolic disturbances or under such conditions set up by injections of hypotonic or hypertonic solutions, that osmosis plays an important role in changing the cerebrospinal fluid pressure. (2) The cerebral blood f...
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