Studies in Specific Hypersensitiveness

Abstract

Summary The typical vesicular lesion of Dermatitis venenata can be produced by means of an alcoholic or chloroform extract of the fresh leaves of Toxicodendron radicans, applied to the skin surface. In our hands, the typical vesicular lesion of Dermatitis venenata could not be produced by the intradermal injection of an active alcoholic extract. The lesion thus produced was not different from that caused by the intradermal injection of the solvent. With the patch test, differences can be demonstrated in the susceptibility of different individuals to poison ivy, and in the incubation period of the lesion. With the technic used, infants could not be shown to be susceptible.