Abstract

Summary. The incorporation of[1‐14C]acetate,[U‐14C]glucose and [1‐14C]palmitate into lipids of red cells from 5‐, 30‐ and 180‐day‐old mice has been studied. The results show that the cells from 5‐ and 180‐day‐old mice have greater capacity for lipid synthesis than those from 30‐day‐old animals. Ghost preparations exhibit a similar pattern of incorporation but the levels of incorporation are higher than those of intact cells. There arc age‐dependent differences in the incorporation of the precursors into various types of lipids. The results show that there are changes in the levels of free fatty acids and triglycerides of red cells as a function of animal age. No quantitative changes were observed in phospholipids and cholesterol.

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