Stuck fragment of totally implantable central venous access ports during removal: risk factor analysis in children

Hanna Jung,Joon Yong Cho,Youngok Lee,Yangki Seok

doi:10.1186/s12893-021-01271-7

Abstract

BackgroundTotally implantable central venous access ports (TICVAPs) have increasingly been used in pediatric patients because they provide reliable venous access. However, many complications associated with TICVAPs have been reported. Here, we aimed to analyze the risk factors of stuck fragment of TICVAPs during removal in children and recommend the appropriate periods of use or exchange.MethodsWe retrospectively reviewed the medical records of 121 patients, including 147 cases of TICVAP insertion, between January 2010 and July 2020.ResultsAmong these, 98 cases in 72 patients involved of TICVAP removal, with 8 patients having had incomplete TICVAP removal resulting in a stuck fragment of the catheter in the central venous system (Group S). All Group S patients were male and had acute leukemia, and their TICVAPs were used for chemotherapy. Compared with the complete removal group (Group N), stuck fragment in Group S were significantly found in patients diagnosed with acute leukemia than those with other diagnoses (p < 0.001). Indwelling duration and body weight change during TICVAP indwelling were significantly longer and larger in Group S, respectively (p < 0.001). In multivariate logistic regression analysis, indwell duration (odds ratio [OR], 1.13; 95% confidence interval [Cl] 1.02–1.37, p = 0.10), body weight change during indwell (OR, 1.00; 95% Cl 0.83–1.18, p = 0.97), and platelet count at TICVAP insertion (OR, 0.98; 95% Cl 0.95–0.99; p = 0.48) showed an increased trend of risk for a stuck catheter.ConclusionsWe suggest prophylactic catheter exchange before indwell duration of 46 months (area under the curve [AUC], 0.949; 95% Cl 0.905–0.993) and body weight change up to 9.9 kg (AUC, 0.903; 95% Cl 0.840–0.966) to prevent a catheter from becoming stuck, especially in children with rapidly growing acute leukemia. Management of a stuck fragment remains controversial in asymptomatic patients, and we suggest careful, close observation rather than aggressive and invasive treatment.

Highlights

Implantable central venous access ports (TICVAPs) have increasingly been used in pediatric patients because they provide reliable venous access
Characteristics of patients and totally implantable central venous access port (TICVAP) A total of 147 cases of TICVAP insertion were performed in 121 patients
13 were still using their TICVAP at the end of the study period, 15 died with their TICVAP still inserted, 18 were transferred to another hospital, and 3 patients had their TICVAP removed in another hospital

Summary

Introduction

Implantable central venous access ports (TICVAPs) have increasingly been used in pediatric patients because they provide reliable venous access. A totally implantable central venous access port (TICVAP), known as a chemoport or cancer port, is a small reservoir connected to a venous catheter positioned in the subcutaneous or muscle layer. TICVAPs have increasingly been used in the field of pediatric oncology to provide reliable vascular access [1]. The catheter portion of the TICVAP can be firmly adhered and stuck to the vessel wall, making the removal of the entire catheter difficult. In such circumstances, excessive pulling force can fracture the catheter, leaving a portion retained in the vessel.

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