ST-Segment Resolution and Global Longitudinal Strain as Predictors of LV Remodeling in Patients with ST-Segment Elevation Myocardial Infarction (STEMI)

Abstract

left ventricular (LV) remodeling after acute myocardial infarction (AMI) is a feared prognostic sequence. Objectives: our goal was to study the possibility of using speckle tracking imaging (STI), especially, global longitudinal strain in predicting LV remodeling. Methods: A total of 82 AMI patients were included in this study. During the first hospital admission after first AMI and at a 6-month follow-up, two-dimensional echocardiography was done. The data was analyzed offline. LV remodeling was defined as ≥15% increase from the baseline LV end-diastolic volume. Results: 34.1% with LV remodeling at 6-month follow-up had similar baseline clinical and echocardiographic characteristics to those without remodeling, except for a predominance of the anterior wall MI (P<0.01), decreased ejection fraction (P<0.05), increased end-systolic volume (P<0.05), and decreased global systolic Ls (P<0.05). Multivariable logistic regression analysis proved that systolic Ls is an independent predictor of remodeling after AMI. Conclusions. Our work has shown that LV longitudinal strain measured by STI is an efficient predictor of LV remodeling after AMI.