Abstract
Three novel isoquinoline alkaloids, TMC-120A, B and C ( 1–3) have been isolated from a fermentation broth of Aspergillus ustus (Bain.) Thom & Church TC 1118, a fungus isolated from rhizosphere of grass. Their structures were determined through extensive spectroscopic analyses and chemical studies. TMC-120s ( 1–3) are found to be the first furo[3,2- h]isoquinoline-type alkaloids isolated from natural sources.
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