Abstract
Electric fields and electrostatic potentials around certain molecules which exhibit varying degrees of anti-HIV (anti-AIDS) activity, namely AZT, CS85, CS87, DDC and two fluorine-substituted analogues of AZT, have been studied. The calculations were performed using net charge distributions obtained by the MNDO method. The results indicate that the presence of a localized electric field region around C5 and an extended electric field region around C3' may be related to the anti-HIV activity.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
