Abstract
The past year has seen several advances in the analysis of the HLA class I region and some of its resident genes. A description of the human class I gene family and the cloning of the class I region in yeast artificial chromosomes have provided two steps forward in the analysis of the class I region. Advances have been made in understanding the expression of the non-classical HLA class 1b genes and work with the murine class 1b proteins has demonstrated that these antigens can present a specialized subset of peptides to the immune system.
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