Abstract
Studied of macro- and microstructure of kidney, liver and spleen of female and male rats did not show significant deviations from such structures of the control group. It has been found that structure of spleen follicles of female and male control groups of rat is better expressed comparing to those whose diet included soybean. The animals whose diet included both conventional and transgenic soybean were found to have a slight increase of Bowman’s capsule in kidney tissues enabled by glomerulus reduction that is apparently due to the effect of both soybean varieties of biologically active components on water-salt metabolism in animals. Considering that the internal structure was preserved and conformed with the norms for animals of given species and age in both control and experimental female and male rat groups, a conclusion on the absence of significant negative or positive effect of GM soybean components on the histological structure of liver, spleen and kidneys can be proposed. Keywords: genetically modified soybean, histology of internals, liver, spleen, kidney.
Highlights
During recent years there is a widespread use of transgenic plants characterized by high resistance to herbicides, pathogenic agents or insect pests, the question of the safety of their influence on human or animal body unclear remains opened [1, 2]
An objective of our work was to study the effect of conventional and GM soybean feeding on growth and microstructure of the internal organs of the first generation of female and male rats
Other researches conducted on young (2–8 months) and adult (24 months) mice fed with GM soybean revealed some hepatocyte nuclei modifications due to transcription/splicing disturbances, as well as some morphofunctional changes in mitochondria [19, 20]
Summary
During recent years there is a widespread use of transgenic plants characterized by high resistance to herbicides, pathogenic agents or insect pests, the question of the safety of their influence on human or animal body unclear remains opened [1, 2]. A transmissibility of transgenic DNA from GM crops to animal organisms, as well as direct effect of toxic and allergenic transgenic proteins, pleiotropic effect on plant metabolism, possible accumulation of herbicides and metabolites in resistant varieties and types of agricultural plants points out a necessity of long-term experiments. It was found that some varieties of GM maize (NK 603, MON 810, MON 863) are characterized by hepatorenal toxicity, associated with possible accumulation of herbicides [13,14,15]. This points out a necessity for further studying of internals histological structure during a long-term feeding of glyphosatetolerant GM plants varieties. An objective of our work was to study the effect of conventional and GM soybean feeding on growth and microstructure of the internal organs (liver, spleen and kidney) of the first generation of female and male rats
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
