Abstract

IN the structure determination of deoxyribonucleic acid (DNA), the method of molecular model building must be combined with that of X-ray diffraction because of the overlap and weakness of the small spacing spots on the DNA X-ray diffraction pattern1,2. For this reason, accurate knowledge of the component parts of the DNA molecule is necessary. The dimensions of the guanine molecule have now been determined with high accuracy from a study of the structure of its hydrochloride.

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