STRUCTURE OF 5'-CHLORO-5,5''-DIFLUORO-1H,1''H- (3,3':3',3''-TERINDOL)-2'(1'H)-ONE

Abstract

The title compound 5'-chloro-5,5''-difluoro-1 H ,1'' H -[3,3':3',3''-terindol]-2'(1' H )-one synthesized via one-pot multicomponent reaction (MCR) at room temperature using commercially available sulfamic acid as inexpensive and environmentally benign organo-catalyst. It crystallizes in the monoclinic space group P 21 with the unit-cell parameters: a= 10.193(5), b= 9.012(5), c= 13.406(5) A, β = 102.767(5) o and Z = 2. The crystal structure was solved by direct methods using single-crystal X-ray diffraction data collected at room temperature and refined by full-matrix least-squares procedures to a final R-value of 0.0390 for 1972 observed reflections. The molecules within the unit cell are stabilized by N-H..O and C-H..F type of hydrogen bonding. The sulphur atom of DMSO solvent molecule is found disordered over two set of sites S100 and S200 with occupancy ratio 0.70:0.30