Abstract
Utilization of (2)H, (13)C, and (15)N isotopically labeled proteins and peptides is now routine in biomolecular NMR investigations. The widespread availability of inexpensive, uniformly (13) C enriched glucose now makes it possible to isolate uniformly (13)C labeled natural products from microbial fermentation. We now wish to describe an approach for the rapid structural characterization of uniformly (13)C labeled natural products that avoids the pitfalls of relying on parameters typically employed in biomolecular NMR studies.
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