Abstract

In article number 2003558 by Hongze Liao, Houwen Lin, Yourong Duan, and co‐workers, first class of APP/DR6 inhibitor, polymer–peptidomimetic PEG‐tAHP‐DRI, are developed by utilizing three rationaldesigned screening strategies, which demonstrate promising anti‐hematogenous metastatic activity by inhibiting the binding of amyloid precursor protein (APP) and death receptor 6 (DR6) as well as blocking the necroptosis of vascular endothelial cells induced by tumors cells.

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