Structure- and Functionality-Based Molecular Design of Azoles and Thiophenes

Abstract

Abstract Heteroaromatic structures are widely found in a variety of organic molecules such as π-extended oligomers/polymers, pharmaceutical drugs, agrochemicals, etc. Considerable efforts have been made for the wide use of heteroaromatic compounds. It is therefore of great interest to develop efficient and practical synthetic methodology in organic chemistry. In this account, the focus is on the molecular design of five-membered heteroaromatic compounds such as azoles and thiophenes covering transition metal-catalyzed carbon–carbon and carbon–heteroatom bond formation at the C–H bond, polymerization reactions employing coupling reactions, and a new class of structural design of heterobiaryls showing molecular asymmetry.