Abstract

The ribosome is a cell organelle that is essential for protein synthesis. That the ribosomes provide sites for the binding of mRNA and the amino-acyl tRNA has been established (see reviews by Watson [1, 2]). In addition, the structural complexity of ribosomes suggests greater complexity in function and, in fact, there are several indications that the structure of ribosomes is profoundly involved in the translation of the genetic code [3, 4, 5]. Recent experiments also suggest that the peptidyl transferase is a part of 50 S ribosomal proteins [6, 7]. However, the detailed function of ribosomes in protein synthesis is still unclear. It appears that a comprehensive understanding of the mechanism of protein synthesis must await an elucidation of the structure and function of ribosomes.

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