Abstract
A macromolecule cross-reacting with antihuman IgD was detected by radial immunodiffusion in the sera of patas, rhesus and macaque monkeys. Sera from chimpanzees and the one baboon tested also showed this reactivity. Physicochemical studies demonstrated that this cross-reacting molecule from the chimpanzee is of similar molecular weight as human IgD and has antigenic characteristics of delta chains. Based on our data, we propose that these nonhuman primates possess an immunoglobulin comparable with human IgD.
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