Abstract

The present invention provides microfluidic systems, which have structurally programmable (PFD), reconfigurable, and multi-sample analysis capabilities. In one embodiment, the device includes structurally programmable fluidic paths, passive microvalves (30), fluidic components based on hydrophobic microfluidic systems (PFD), and pneumatic actuators using an air-bursting actuation concept. By controlling both the length and surface properties (e.g., hydrophilic or hydrophobic) of the channels (14), the pressure drops through the designed microfluidic systems will be controlled and thus programmable.

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