Abstract
Background: Decreased efficiency of artemisinin combination therapy (ACT) and the declining efficacy of affordable drugs for malaria is a major concern with half of the world population living in countries endemic to the disease; hence the development of the next generation anti-malarial drugs is the need of the hour. Keywords: Malaria, Plasmodium falciparum, X-prolyl aminopeptidase, homology modelling, molecular dynamics simulation.
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