Abstract
ABSTRACT The present study reports a novel technique to synthesise silica nanoparticles through modified sol-gel, ultrasonication, and hydrothermal routes. Physio-chemical and structural characterization was carried out using X-ray diffraction, high resolution scanning electron microscopy, energy dispersive spectroscopy, dynamic light scattering, Fourier transform infrared spectroscopy, ultraviolet-visible, and photoluminescence spectroscopy. The particle size determination revealed the spherical structure of nanoparticles with an average diameter of 85 nm and between 90-170 nm through HRSEM and DLS respectively. Stretching and vibration bands confirming the presence of SiO2 were obtained in FTIR analysis. Spectra from UV-vis and PL spectroscopy were obtained at a maximum wavelength of 233 nm and 555 nm respectively. The anti-microbial effect of SiO2 nanoparticles against E. coli and S. aureus bacteria revealed the appreciable response which renders them for many biomedical applications like drug delivery. The cytotoxicity of SiO2 nanoparticles on human lung epithelial (A549) cell line revealed their non-toxic behavior.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
