Abstract
The acute renal failure syndrome (ARF) may result from a variety of causes. This discussion will focus on one of the major subtypes of this entity, specifically that of acute tubular necrosis (ATN) which by definition includes those forms of acute renal failure in which tubular injury of acute onset is the primary basis for renal failure, and excludes other causes of ARF, such as those due to glomerular, vascular and interstitial lesions. ATN is by far the most common cause of ARF, and accounts for some 40% of cases encountered clinically.
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