Abstract
Two new trisaccharides, chrysostosides A and B (1‒2), and a new natural product, chrysostorine (3), together with six known compounds (4‒9) were isolated from the sea snail Turbo chrysostomus. Their structures were elucidated based on interpretation of NMR and HRESIMS data and by comparison of the spectral data with those reported in the literature. The relative configurations of 1 and 2, and the structure of 3 were deduced from 2D NMR experiments and quantum chemical calculations, including the computed JH,H coupling constants, 1H and 13C NMR chemical shifts with DP4+ predictions. All isolated compounds were evaluated for their antimicrobial activity. Among them, compound 4 showed moderate activity against Enterococcus faecalis and Staphylococcus aureus with MIC value of 32 μg/mL.
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