Structural Biomimetic Scaffold Modifications for Bones

Abstract

Over the years, biomimetic scaffolds have been commonly used in the process of tissue regeneration for treatment of bone defects. Even though current biomimetic scaffolds are easily accessible, they lack mechanical strength for ideal applications. This research aims to improve on current designs to create new three-dimensional biomimetic scaffolds for bones. Different biomimetic scaffolds were designed and 3D-printed and was tested for mechanical strength conducting a tensile strength test on the scaffolds. The tests show that the scaffold with hexagonal pores proved to be the most effective scaffold due to its geometrical properties which allows it to withstand more pressure. This was concluded according to the spread of pressure along the scaffold that is dependent on the amount of pressure exerted, and the identification of first fracture which affects the line of breakage across the entire scaffold. This research is able to better help extend the field of tissue engineering and the applicability of 3D biomimetic bone scaffolds for clinical usage.