Abstract

The three-dimensional structures of myosin subfragment 1 (S1), gelsolin segment 1 complexed with α-actin, villin fragment 14T, Acanthamoeba profilin-1, and bovine profilin complexed with β-actin were completed last year. Together, they expand our understanding of the structural organization of actin-binding proteins. In additioin, the segment 1 and bovine profilin complexes provide atomic-level descriptions of their interfaces with actin.

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