Structural and spectral studies of thiosemicarbazones derived from 3- and 4-formylpyridine and 3- and 4-acetylpyridine

Abstract

Crystal structures of thiosemicarbazones prepared from 3- and 4-formylpyridine and 3- and 4-acetylpyridine are included along with their UV spectra. 4-Formylpyridine thiosemicarbazone has the following structural properties: monoclinic, P21/n, a=7.2420(5), b=13.961(1), c=8.415(1)Å,β=90.90(1)°, V=850.7(1)Å3 and Z=4; for 3-formylpyridine thiosemicarbazone: monoclinic, C2/c, a=13.661(2), b=7.1120(4), c=19.046(2)Å,β=107.71(1)°, V=1762.8(3)Å3 and Z=8; for 4-acetylpyridine thiosemicarbazone: triclinic, P-1, a=8.104(3), b=8.512(2), c=8.708(3)Å,α=83.85(0), β=66.66(0), γ=62.87(0)°, V=488.9(3)Å3 and Z=2; for 3-acetylpyridine thiosemicarbazone monoclinic, P21/a, a=8.408(1), b=11.853(2),= c=9.777(3)Å,β=97.66(2)°, V=985.7(4)Å3 and Z=4. Intramolecular and intermolecular hydrogen bonding are both present. There is a difference in the angles between the mean planes of the pyridine ring and thiosemicarbazone moiety in the two series.