Structural and organometric changes of the uterus in conditions of dark deprivation

Abstract

The effect of 30-day dark deprivation (light-dark cycle 24/0 h, artificial illumination 300 Lux) and 14-day correction with melatonin on the endometrium of the uterus was studied in an experiment on mongrel females of 4 months of age. It was found that 30-day dark deprivation leads to hyperplastic processes of the endometrium: an increase in the number of uterine glands (by 18.9 % p 0.05), thickening of the endometrium (by 12.5 %, p 0.05). Morphometric characteristics of the endometrium: single-layer columnar epithelium of the endometrium and uterine glands were corrected by administration of exogenous melatonin for 14 days.