Östrogenabhängige Erkrankungen der weiblichen Genitalorgane und Adipositas - der Fall eines Endometriumkarzinoms

Abstract

Prolonged exposure to unopposed estrogens has a proliferative effect on the endometrium and can induce endometrial carcinoma. We describe a massively obese postmenopausal woman with high levels of endogenous estrogens who developed proliferative changes in the ovaries and the uterus in addition to endometrial hyperplasia and carcinoma. This case underlines the importance of primary prevention of gynecologic conditions and of the use of progestins in postmenopausal women.