Abstract
The patient here referred to has an idiosyncrasy for two drugs, quinin and cocain. Such susceptibility to quinin has been frequently reported, and I have seen several cases so afflicted, but I am not aware of any one being affected by cocain in this manner, and a cursory examination of the literature fails to reveal a similar case. During January, in testing the refraction of L. L., a bank clerk, aged 25, I had a nurse in the office instil a solution of homatropin, gr. ½, in ½ dram of 4 per cent. solution of cocain, one drop in each eye, repeated every five minutes until six drops were used. Just before using the last drop the nurse called my attention to the fact that the patient's eyes had become very much swollen. To my astonishment I found the lids so swollen that it was only after the greatest effort
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