Abstract

Abstract 1. Experiments were conducted with juvenile Clarias lazera to investigate the influence of acute copper exposure on bioaceumulation and some haematological constituents (erythrocyte count, haemoglobin content and haematocrit value). 2. Analyses of copper residues in liver, kidney, muscle, gills, brain and blood after 96-hr exposure period revealed that liver and kidney accumulated the greatest amount of copper, while the other organs were found to accumulate relatively smaller concentrations. 3. All blood samples collected from copper-treated fish showed some haemolysis. In addition, significant decreases in the values of the 3 parameters were noted. The anaemia reported is therefore of the haemolytic type, possibly due to the effect of copper on membrane ATPase, the glycolytic enzymes in the erythrocytes and glutathione.

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