Abstract
A method for determining stress resistance is employed for the investigation of a possible difference between thymectomized and normal animals with respect to their abilities to withstand the stressing effects of various nonspecific stressor agents. Rats are used as the test animals, and the experimental data evaluated by the Litch-field-Wilcoxon method. Evidence is provided to indicate that there is no significant difference in the ability of normal and thymectomized groups to withstand the stressing effects of dry heat, reserpine, and histamine. The restoration of normal stress resistance in thymectomized, adrenalectomized animals receiving adrenal cortical extracts is not dependent upon the process of thymus involution.
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