Abstract
Stress resistance, heterogeneity and mortality plateaus: response by the authors
Highlights
Service has focussed on one model of environmental heterogeneity in discussing the results of our paper, which we call the variance-in-A model
This happens because well before an asymptote is reached the rate of increase in mortality rates slows and the observed mortality rates start to depart from the Gompertz predictions
Since frailty is assumed to be due to differences in A this confidence interval suggests that micro-environmental variation can cause some individuals to have values of A that are less than the population mean by a factor of 40
Summary
Service has focussed on one model of environmental heterogeneity in discussing the results of our paper, which we call the variance-in-A model. The mortality rate of individuals aged-x in such a population is given by, m x When this is done for large cohorts the resulting model predicts the timing of mortality fairly well except for a prediction of a small class of very old individuals that are not observed (Rose and Mueller, 2000).
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