Stress Relaxation Phenomenon in the Healthy Female Urethra

Abstract

Following dilatation, urethral pressure declines over the next few seconds to a state of equilibrium. The stress relaxation parameter, Pt0.5, was defined as the relative pressure decrease 0.5 s after dilatation, where the pressures at 0.1 s and at the new equilibrium were set to 100% and 0% respectively. Pt0.5 was calculated from 171 urethral dilatations performed at each of 3 urethral sites of measurement in 10 healthy volunteers. It was found to be independent of the rate and size of urethral dilatation. It showed a fairly high reproducibility rate when repeated after 1 h and 1 week. Pt0.5 was calculated to approximately 60% with no variation along the urethra. The parameter is assumed to be useful in evaluating urethral sphincter function. Although the method can be performed without special urodynamic equipment, the frequency response of the pressure measurement system must be adequate.