Abstract
A series of experiments determined the relationship between the internal osmotic balance of rats and the direction and magnitude of stress-induced, body-fluid osmolality (BFO) changes. The state of BFO was varied by food or water deprivation. Two forms of stress were applied: rotation or sham stomach loading. The results indicate that animals deprived of food or water failed to respond to rotation, but deprivation conditions had no influence on the BFO change induced by sham stomach loading. Although the change of BFO in response to nonspecific, stressful stimuli appeared to be in the hyperosmotic direction, the magnitude of BFO increase was a function of the severity of stress and the state of BFO.
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