Abstract
Background A recent large-scale clinical trial has indicated that an initial invasive strategy does not improve cardiac outcomes beyond optimized medical therapy in patients with stable coronary artery disease (CAD). Therefore, novel methods to stratify at-risk patients may refine therapeutic decisions and improve outcomes. We sought to test the hypothesis that stress cardiac magnetic resonance (CMR) imaging effectively prognosticates and reclassifies patient risk in a consecutive clinical cohort of patients with known or suspected CAD across a spectrum of guideline-determined risk categories.
Highlights
A recent large-scale clinical trial has indicated that an initial invasive strategy does not improve cardiac outcomes beyond optimized medical therapy in patients with stable coronary artery disease (CAD)
In a prospective observational study of 815 consecutive patients clinically referred for stress cardiac magnetic resonance (CMR) between 2001-2011, we studied the association of inducible ischemia on a composite of cardiac mortality and acute non-fatal myocardial infarction (MACE)
Inducible ischemia was the strongest predictor of MACE in the overall cohort and in patients with prior CAD
Summary
Jiazuo H Feng*, Ravi Shah, Bobby Heydari, Venkatesh L Murthy, Siddique Abbasi, Tomas G Neilan, Ron ABlankstein , Marcelo Di Carli, Michael Jerosch-Herold, Raymond Y Kwong. From 16th Annual SCMR Scientific Sessions San Francisco, CA, USA. From 16th Annual SCMR Scientific Sessions San Francisco, CA, USA. 31 January - 3 February 2013
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