Abstract

EXPERIENCES with streptomycin therapy of infections in United States Army hospitals have been reported from time to time.<sup>1</sup>The purpose of this communication is to present the results of streptomycin therapy in a group of 37 patients with otitis externa, otitis media, mastoiditis, brain abscess and meningitis. All the patients were treated in United States Army hospitals, the majority at Halloran General Hospital. The prognosis of infection of the ear and adjacent structures has improved markedly since the advent of the sulfonamide compounds and penicillin. However, the management of these entities per se, especially when they are in combination one with the other, still presents a challenge to the physician. Many of the causal organisms are refractory to penicillin and to the sulfonamide compounds, either because of natural resistance or because of acquired fastness resulting from inadequacy of contact with lethal concentrations of the drug or from inadequacy of dosages

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