Abstract

SummaryBoth streptomycin and diasone are therapeutically effective in the treatment of experimental tuberculosis of guinea pigs. Both are more effective in suppressing tuberculous infection by the institution of treatment within a few days after inoculation with virulent tubercle bacilli than in the treatment of established lesions developing 2 weeks or longer after infection has been established. Particularly noteworthy therapeutic results were observed following combined streptomycin and diasone therapy, suggesting that these 2 compounds exert a synergistic or additive therapeutic effect in the treatment of experimental tuberculosis.

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