Abstract
The development of dental caries is affected by various factors. Patient's general health status can affect the risk of caries. Some systemic diseases may improve caries incidence or cause dental caries by changing oral microenvironment, affecting salivary gland function and salivary composition, and destroying dental structure directly or indirectly. The clinical symptoms and signs of caries associated with systemic diseases are different from common caries and this type of caries has its special strategy of prevention and therapy. The present review article analyzes the causes and mechanisms of caries susceptibility in patients receiving systemic therapy and systematically introduce the modern concepts of caries prevention and management in systemic therapy.
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