Abstract
Individuals with neural damage hope to regain their impaired functions. However, therapeutic rehabilitation is lacking. Nishimura et al. (2013) have documented that the strength of neural connections between the motor cortex and the spinal cord can be modified using an autonomous recurrent neural interface that delivers electrical stimuli in the spinal cord and this is triggered by action potentials of corticospinal cells during free behavior. This activity-dependent stimulation modifies the strength of the terminal connections of single corticomotoneuronal cells, which is consistent with the bidirectional spike-timing-dependent plasticity rule previously derived from in vitro experiments. The success of our protocol suggests neurorehabilitative treatments could be possible for patients with damaged pathways.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
