Abstract
SummaryBioelectric charge transfer at the blood-wall interface may be a crucial factor affecting thrombosis on implant materials. The in-vitro streaming potential test technique offers a very sensitive, yet simple, means for observing this interfacial electrokinetic charge phenomena. Particular attention to test control variables is required, however, to obtain valid, comparative results. Due to the dynamic, changing nature of some surfaces on the molecular scale, reproducibility of results is subject to question and necessitates repeated runs to gain assurance of results.It is demonstrated that this method of evaluation is an extremely sensitive tool in the study of blood-surface inter-actions. Changes in streaming potentials are dramatically revealed upon introduction of minute quantities of blood protein elements and drugs affecting blood coagulation. The techniques for applying this test method to the study of thrombosis are illustrated.Streaming potential testing is a possible tool for realizing quality control in the preparation of anti-thrombogenic materials for cardiovascular implants. It may serve as a check, both on the formation of a proper surface and on the stability of this surface under physiological environment conditions.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
