Strategy in Optimization of Silicone Oil Emulsion by D-Optimal Mixture Design

Abstract

Silicon oil emulsion was prepared by mixing silicon oil with emulsifiers and water. To optimize the emulsifiers formulation, the D-optimal mixture design (DMD) in Design-Expert software was used to design the emulsifiers formulation. E-1304, AEO-3, SG-6and OP-10 were used as emulsifiers. According to the mixture design matrix given by Design Expert 8.0.5, 20 samples of silicon oil emulsion were prepared, and their stabilities were investigated. Through the establishment of the regression model, the analysis of the interaction among the variables and operating the optimization functions of the mixture design software, an optimized emulsifier formulation was given, and with which a silicon oil emulsion with high solid content (56%) and good stability was prepared.