Strategies for intrapartum foetal surveillance in low- and middle-income countries: A systematic review.

Natasha Housseine,Kerstin Klipstein-Grobusch,Tarek Meguid,Diederick E Grobbee,Marcus J Rijken,Barbara E Kwast,Arie Franx,Joyce L Browne,Marieke C Punt,Stephan Brenner

doi:10.1371/journal.pone.0206295

Abstract

BackgroundThe majority of the five million perinatal deaths worldwide take place in low-resource settings. In contrast to high-resource settings, almost 50% of stillbirths occur intrapartum. The aim of this study was to synthesise available evidence of strategies for foetal surveillance in low-resource settings and associated neonatal and maternal outcomes, including barriers to their implementation.Methods and findingsThe review was registered with Prospero (CRD42016038679). Five databases were searched up to May 1st, 2016 for studies related to intrapartum foetal monitoring strategies and neonatal outcomes in low-resource settings.Two authors extracted data and assessed the risk of bias for each study. The outcomes were narratively synthesised. Strengths, weaknesses, opportunities and threats analysis (SWOT) was conducted for each monitoring technique to analyse their implementation.There were 37 studies included: five intervention and 32 observational studies. Use of the partograph improved perinatal outcomes. Intermittent auscultation with Pinard was associated with lowest rates of caesarean sections (10–15%) but with comparable perinatal outcomes to hand-held Doppler and Cardiotocography (CTG). CTG was associated with the highest rates of caesarean sections (28–34%) without proven benefits for perinatal outcome. Several tests on admission (admission tests) and adjunctive tests including foetal stimulation tests improved the accuracy of foetal heart rate monitoring in predicting adverse perinatal outcomes.ConclusionsFrom the available evidence, the partograph is associated with improved perinatal outcomes and is recommended for use with intermittent auscultation for intrapartum monitoring in low resource settings. CTG is associated with higher caesarean section rates without proven benefits for perinatal outcomes, and should not be recommended in low-resource settings. High-quality evidence considering implementation barriers and enablers is needed to determine the optimal foetal monitoring strategy in low-resource settings.

Highlights

Over two million stillbirths are estimated to occur yearly worldwide, of which >98% are in low-resource settings [1,2]
The partograph is associated with improved perinatal outcomes and is recommended for use with intermittent auscultation for intrapartum monitoring in low resource settings
CTG is associated with higher caesarean section rates without proven benefits for perinatal outcomes, and should not be recommended in low-resource settings

Summary

Introduction

Over two million stillbirths are estimated to occur yearly worldwide, of which >98% are in low-resource settings [1,2]. Almost half of the number of stillbirths in low- and middle-income countries (LMICs) occur during labour, whereas most stillbirths in high-income countries (HICs) take place during the antenatal period [3,4]. Methods of foetal surveillance include foetal heart rate (FHR) monitoring by intermittent auscultation (IA), cardiotocography (CTG) with foetal blood sampling and foetal electrocardiogram with ST-wave analysis [10,11]. The majority of the five million perinatal deaths worldwide take place in low-resource settings. In contrast to high-resource settings, almost 50% of stillbirths occur intrapartum. The aim of this study was to synthesise available evidence of strategies for foetal surveillance in low-resource settings and associated neonatal and maternal outcomes, including barriers to their implementation

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Methods

Results

Discussion

Conclusion