Stranger sociability in preterm infants with very low birth weight and term infants

Abstract

55.2± 6.51; BMI: 22.5± 1.4) were recruited in this study. BMI of the knee OA group was significant higher when compared to the control group (p< 0.001). Baseline lateral tibial cartilage thickness was significant higher in asymptomatic controls compare to knee OA group (p= 0.045). There were no significant difference in age, cartilage property and cartilage morphology in other regions between groups. Two-way mixed ANOVA revealed no significant differences on cartilage property and morphology changes before and after dynamic loading between groups. Both groups showed significant decreased T2 relaxation time in medial femoral cartilage region (35.83± 12.41ms vs. 29.17± 10.9ms) after stepping, increased medial tibial cartilage volume (1.4± 0.27mm vs. 1.45± 0.26mm) between M2 (post loading 7min) and M4 (post loading 21min). Lateral tibial cartilage volume and thickness were significant difference between knee OA group and control group. Conclusion(s): There were no significant differences in cartilage property andmorphology between kneeOApatients and asymptomatic controls before and after ten minutes stepping. Decrease T2 relaxation time inmedial femoral cartilage regionwas identified in both group after tenminutes dynamic loading. Implications: This was the first in vivo study to observe knee cartilage changes after dynamic loading in both individuals with kneeOA and asymptomatic controls. Future studies could investigate effects of different loading magnitudes, correlation between cartilage deformation and recovery in healthy population with a larger sample size.