Abstract
BackgroundRecently introduced fast strain-encoded (SENC) cardiac magnetic resonance (CMR) imaging (fast-SENC) provides real-time acquisition of myocardial performance in a single heartbeat. We aimed to test the ability and accuracy of real-time strain-encoded CMR imaging to estimate left ventricular volumes, ejection fraction and mass.MethodsThirty-five subjects (12 healthy volunteers and 23 patients with known or suspected coronary artery disease) were investigated. All study participants were imaged at 1.5 Tesla MRI scanner (Achieva, Philips) using an advanced CMR study protocol which included conventional cine and fast-SENC imaging. A newly developed real-time free-breathing SENC imaging technique based on the acquisition of two images with different frequency modulation was employed.ResultsAll parameters were successfully derived from fast-SENC images with total study time of 105 s (a 15 s scan time and a 90 s post-processing time). There was no significant difference between fast-SENC and cine imaging in the estimation of LV volumes and EF, whereas fast-SENC underestimated LV end-diastolic mass by 7%.ConclusionThe single heartbeat fast-SENC technique can be used as a good alternative to cine imaging for the precise calculation of LV volumes and ejection fraction while the technique significantly underestimates LV end-diastolic mass.
Highlights
Introduced fast strain-encoded (SENC) cardiac magnetic resonance (CMR) imaging provides real-time acquisition of myocardial performance in a single heartbeat
Study participants with suspected or confirmed coronary artery disease (CAD) were significantly older than the healthy volunteers (61.37 ± 10.93 y vs. 28.67 ± 4.89 y, p < 0.001)
LVEDV and LVESV were similar in both groups, whereas LVSV and LVEF were significantly lower in CAD patients (LVSV: 80.48 ± 17.81 ml vs. 97.00 ± 18.96 ml, p = 0.021; LVEF: 52.09 ± 11.29% vs. 59.75 ± 1.36%, p = 0.034)
Summary
Introduced fast strain-encoded (SENC) cardiac magnetic resonance (CMR) imaging (fastSENC) provides real-time acquisition of myocardial performance in a single heartbeat. We aimed to test the ability and accuracy of real-time strain-encoded CMR imaging to estimate left ventricular volumes, ejection fraction and mass. Cine cardiac magnetic resonance (CMR) is the accepted standard of reference for quantification of ventricular volumes, mass and function [1]. According to recent recommendations quantification of left ventricular (LV) volumes is performed using manual contouring of the endocardial and epicardial surface from multiple short-axis planes and LV ejection fraction (EF) and mass are calculated. The aim of this pilot study was to assess the ability and accuracy of recently proposed fast-SENC technique to estimate LV volumes, ejection fraction and end-diastolic mass.
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