Abstract
This study introduces a novel hydroxymethylation method using DMSO. A wide range of 1,3-dicarbonyls underwent hydroxymethylation efficiently to afford the corresponding hydroxylated products in yields ranging from 73 % to 98 % under basic conditions, with formaldehyde generated from DMSO decomposition catalyzed by oxalyl chloride and hydrochloric acid in 1,4-dioxane. This method offers a more efficient alternative to existing approaches, expanding synthetic possibilities.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
