Abstract

AbstractThis Rosarium Philosophorum essay tells the story of the author's “conversion” to a theorist, and then the events which led him to stumble over valence bond (VB) theory, and his developments of “VB diagrams” as conceptual tools which enable one to describe all chemical reactions. The story continues to the adventure with the enzyme Cytochrome P450, and how this interest led eventually the author to treat the reactivity of this enzyme using VB diagrams. And finally, the essay describes the author's struggle with complexity through molecular dynamics of these enzymes. This is also a story of interactions between individuals who seek insight and wisdom and how they influence one another through friendships and teacher‐disciples relations. This is the key wisdom one garners through scientific life.

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