Stomach-specific mucoadhesive microsphere as a controlled drug delivery system

Abstract

Stomach-specific mucoadhesive microspheres as a controlled drug delivery system have been developed to increase gastric retention time of the dosage forms. It is known that differences in gastric physiology, such as gastric pH and motility, exhibit both intra- as well as inter-subject variability demonstrating significant impact on gastric retention time and drug delivery behavior. This article presents the polymers use for mucoadhesive microsphere, factor affecting the mucoadhesion, and preparation techniques of mucoadhesive microsphere. Developments in the techniques for in vitro and in vivo evaluation of mucoadhesive microspheres have also been discussed. How to Cite this Article Pubmed Style Rajput G, Majmudar F, Patel J, Thakor R, Rajgor NB. Mucoadhesive Microsphere as a Controlled Drug Delivery SRP. 2010; 1(1): 70-78. doi:10.4103/0975-8453.59515 Web Style Rajput G, Majmudar F, Patel J, Thakor R, Rajgor NB. Mucoadhesive Microsphere as a Controlled Drug Delivery http://www.sysrevpharm.org/?mno=302644633 [Access: March 28, 2021]. doi:10.4103/0975-8453.59515 AMA (American Medical Association) Style Rajput G, Majmudar F, Patel J, Thakor R, Rajgor NB. Mucoadhesive Microsphere as a Controlled Drug Delivery SRP. 2010; 1(1): 70-78. doi:10.4103/0975-8453.59515 Vancouver/ICMJE Style Rajput G, Majmudar F, Patel J, Thakor R, Rajgor NB. Mucoadhesive Microsphere as a Controlled Drug Delivery SRP. (2010), [cited March 28, 2021]; 1(1): 70-78. doi:10.4103/0975-8453.59515 Harvard Style Rajput G, Majmudar F, Patel J, Thakor R, Rajgor NB (2010) Mucoadhesive Microsphere as a Controlled Drug Delivery SRP, 1 (1), 70-78. doi:10.4103/0975-8453.59515 Turabian Style Rajput G, Majmudar F, Patel J, Thakor R, Rajgor NB. 2010. Mucoadhesive Microsphere as a Controlled Drug Delivery Systematic Reviews in Pharmacy, 1 (1), 70-78. doi:10.4103/0975-8453.59515 Chicago Style Rajput G, Majmudar F, Patel J, Thakor R, Rajgor NB. Stomach-Specific Mucoadhesive Microsphere as a Controlled Drug Delivery System. Systematic Reviews in Pharmacy 1 (2010), 70-78. doi:10.4103/0975-8453.59515 MLA (The Modern Language Association) Style Rajput G, Majmudar F, Patel J, Thakor R, Rajgor NB. Stomach-Specific Mucoadhesive Microsphere as a Controlled Drug Delivery System. Systematic Reviews in Pharmacy 1.1 (2010), 70-78. Print. doi:10.4103/0975-8453.59515 APA (American Psychological Association) Style Rajput G, Majmudar F, Patel J, Thakor R, Rajgor NB (2010) Mucoadhesive Microsphere as a Controlled Drug Delivery Systematic Reviews in Pharmacy, 1 (1), 70-78. doi:10.4103/0975-8453.59515