Abstract
The influence of cortisol on the swelling of rat liver mitochondria was studied. An increase of the swelling rate under the influence of cortisol is apparent 12 and 44 minutes after mixing the hormones and the mitochondrial suspension; the effect disappears after a few hours. Maximal acceleration is observed at 10 −9 M cortisol. At this steroid concentration the ratio of cortisol molecules per mitochondrion is approximately 1000:1.
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