Abstract
Abstract This paper deals with the monitoring of physiological state changes that may occur during a culture of a single micro-organism. It rests on a partial measurement of component concentrations in the reactor and of the input and output flows and utilises a stoichiometric approach to model biochemical reactions involved by the culture. We propose to define the basic reaction structure from component compositions and from calculability conditions of the stoichiometric matrix. A given physiological state is associated with a set of basic reactions. The monitoring of a system is then derived from the obtained model by using a bank specialised unknown input observer.
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